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Saúde / 21/07/2021

HEALTH TECHNOLOGY

Scientists Successfully Test Stem Cells for Diabetes Cure

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Scientists Successfully Test Stem Cells for Diabetes Cure

Fonte GNN

Stem Cells to Cure Diabetes! Researchers at the Salk Institute for Biological Studies have devised a new way to produce pancreatic beta cells to treat type 1 chronic disease, characterized by increased blood sugar levels.

After the success with mice, scientists in California, USA, will carry out tests on humans to obtain approval the FDA, the regulatory agency of the United States.

A pharmaceutical company has already joined the team of researchers to produce these cells in the laboratory.

Method

The use of a three-dimensional Petri dish allowed the cells to interact and grow in an environment similar to what they would naturally do in the body.

Two weeks after transplantation in diabetic mice, their blood sugar dropped to normal levels, like those seen in non-diabetic mice.

“Stem cells are an extremely promising approach for the development of many cell therapies. This includes the best treatments for type 1 diabetes,” Salk professor Juan Carlos Izpisua Belmonte, senior author of the corresponding article, told Salk's press department.

cysts disappeared

To test the safety and effectiveness of the manufactured beta cells, the team transplanted them at different stages and looked at the effects.

At the highest stages of growth, cells did not form cysts even 20 weeks after implantation and showed adequate functionality in vivo and in vitro.

The challenge, scientists say, is the manufacture of pancreatic beta cells.

"This method of manufacturing large numbers of functional and safe beta cells is an important step forward," he concluded.


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